Appendix C: WHO Staging System for HIV Infection and Disease in Children
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Pediatric Clinical Stage I:
1. Asymptomatic 2. Generalized lymphadenopathy |
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Pediatric Clinical Stage II:
1. Chronic diarrhea >30 days duration in absence of known etiology 2. Severe persistent or recurrent candidiasis outside the neonatal period 3. Weight loss or failure to thrive in the absence of known etiology 4. Persistent fever >30 days duration in the absence of known etiology 5. Recurrent severe bacterial infections other than septicemia or meningitis (e.g., osteomyelitis, bacterial (non-TB) pneumonia, abscesses) |
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Pediatric Clinical Stage III:
1. AIDS-defining opportunistic infections 2. Severe failure to thrive (wasting) in the absence of known etiologya 3. Progressive encephalopathy 4. Malignancy 5. Recurrent septicemia or meningitis |
Source: World Health Organization. Scaling up antiretroviral therapy in resource-limited settings: treatment guidelines for a public health approach. Geneva: World Health Organization, 2004:62. (Accessed July 9, 2006 at: http://www.who.int/3by5/publications/documents/arv_guidelines/en/index.html.)
a Persistent weight loss >10% of baseline or less than 5th percentile on weight for height chart on two consecutive measurements more than one month apart in the absence of another etiology or concurrent illness.
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